Differentiated Thyroid Cancer in Asians

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Differentiated Thyroid Cancer in Asians

In the past two decades, thyroid cancer has rapidly increased around the world, including in Korea [1]. Although the exact cause of this increase is still under debate, cancer screening with high-resolution ultrasound (US) might have led to earlier diagnosis of smaller thyroid cancers [2-4]. However, the increased incidence across all tumor sizes suggests that a higher rate of detection of smal...

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Mutation Profile of Well-Differentiated Thyroid Cancer in Asians

Recent advances in molecular diagnostics have led to significant insights into the genetic basis of thyroid tumorigenesis. Among the mutations commonly seen in thyroid cancers, the vast majority are associated with the mitogen-activated protein kinase pathway. B-Raf proto-oncogene (BRAF) mutations are the most common mutations observed in papillary thyroid cancers (PTCs), followed by RET/PTC re...

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Thyroid hormone replacement one day before 131I therapy in patients with well-differentiated thyroid cancer

Objective: The current study aimed to determine the efficacy of radioiodine-131 (131I) ablation therapy with thyroid hormone replacement one day before 131I administration in patients with well-differentiated thyroid cancer (DTC). Methods: This retrospective study included 29 patients who underwent 131I therapies twice for DTC during 6-12 months.  Since all the patients obviously had residual l...

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The role of Ile3434Thr XRCC7 gene polymorphism in Differentiated Thyroid Cancer risk in an Iranian population

Background: The aim of this study was to understand any association between differentiated thyroid carcinoma (DTC) and Ile3434Thr XRCC7 gene polymorphism (GenBank accession number: rs7830743). DTC is the most prevalent thyroid neoplasm, which includes papillary and follicular cell carcinoma. XRCC7 gene encodes a protein that functions in non-homologous end joining DNA repair pathway. Non-synony...

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ژورنال

عنوان ژورنال: Endocrinology and Metabolism

سال: 2016

ISSN: 2093-596X,2093-5978

DOI: 10.3803/enm.2016.31.1.62